Main source of pesticide residues in vegetable products is their direct application in the crops to eliminate different types of pest. Due to the low detection levels required by regulatory bodies and the complex nature of the matrices in which the target compounds are present, efficient sample preparation and trace-level detection and identification are important aspects in an analytical method. Multiresidue method development is difficult, due to the fact that compounds of different polarities, solubilities, volatilities and pKa values have to be simultaneously extracted and analysed. Fruit and vegetables are capable of retaining larger quantities of pesticides. Pesticides can accumulate in fruit skins. The crops most exposed to the presence of pesticides are grapes, citrus fruits and potatoes. Adsorbed pesticides can reduce the nutritious value of crops or alter their organoleptic properties. The present-day trend is to move away from persistent pesticides and to apply agents with a short decomposition time. Organochlorine pesticides have been replaced by organonitrogen and – phosphorus pesticides. Currently 520 approved active ingredients are used in nearly 2000 commercial products. These substances belong to more than 100 different classes. It is estimated that EU countries consume more than 300,000 tons of pesticides per annum for .....