uccessful extraction techniques are crucial in many applications to enable the proper analyses of pesticides and herbicides in aquatic, soil, and other media. The extraction techniques can be broadly classified as solid– or liquid–phase extraction or dispersion, with much overlap and other sub–categories, such as microextraction techniques. In solid–phase extraction, Carpinteiro et al. (2010) developed a procedure to extract, purify, and analyze for the fungicides metalaxyl–M, azoxystrobin, myclobutanil, flusilazole, penconazole, tebuconazole, propiconazole, diniconazole and difenoconazole in wine samples using mixed–mode, anion exchange, and reversed– phase, OASIS MAX solid–phase extraction (SPE) cartridges for purification and extraction and analyses using liquid chromatography coupled to tandem electrospray ionization mass spectrometry (LC–ESI–MS/MS). Several commercial wines from Spain were analyzed, and metalaxyl–M and azoxystrobin were found at concentrations up to several µg/L in most samples, with the analytical technique exhibiting a limit of quantification